abstract：:Several cardiorespiratory diseases can complicate human immunodeficiency virus infection. Primary pulmonary hypertension is a rare clinical disorder which carries a bad prognosis. More than 90 cases of HIV-associated primary pulmonary hypertension have been reported to date. Although its pathogenesis remains unknown, ...

journal_title：Postgraduate medical journal

authors： Golpe R,Fernandez-Infante B,Fernandez-Rozas S

更新日期：1998-07-01 00:00:00

abstract：:Prompt restoration of coronary artery patency in acute myocardial infarction is associated with substantial improvements in morbidity and mortality. The pivotal role of thrombolysis and aspirin in achieving these goals is well established. However, despite the success of thrombolytic therapy in large trials, clinical ...

journal_title：Postgraduate medical journal

authors： Mahy IR,Jennings KP

更新日期：1998-06-01 00:00:00

abstract：:A 24 year old woman living in the Mediterranean region of Turkey present with a three-month history of weight loss and irregular fever that was peaking at 40 degrees C with shivering. No definite aetiology could be identified in a local hospital. A bacterial infection had been suspected, but antibiotic therapy, at fir...

journal_title：Postgraduate medical journal

authors： Büyükaşik Y,Ileri NS,Haznedaroğlu IC,Demiroğlu H,Dündar S

更新日期：1998-04-01 00:00:00

abstract：:Under certain circumstances, living wills or advance directives may carry legal force in the UK. This paper traces the development of advance directives, clarifies their current legal position and discusses potential problems with their use. Case histories are used to illustrate some of the common dilemmas which docto...

journal_title：Postgraduate medical journal

authors： Stewart K,Bowker L

更新日期：1998-03-01 00:00:00

abstract：:The introduction of spiral technology to computed tomography (CT) scanners in the late 1980s has revolutionised the field of CT. Spiral CT offers definite practical benefits over conventional scanners and has expanded the role of CT through the development of new scanning techniques. CT scanning now rivals magnetic re...

journal_title：Postgraduate medical journal

authors： Kearney SE,Garvey CJ

更新日期：1998-02-01 00:00:00

abstract：:A case is presented of a young competitive body-builder who abused anabolic steroid drugs and developed profound symptomatic hypogonadotrophic hypogonadism. With the help of prescribed testosterone (Sustanon) he stopped taking anabolic drugs, and later stopped Sustanon also. Hypogonadism returned, but was successfully...

journal_title：Postgraduate medical journal

authors： Gill GV

更新日期：1998-01-01 00:00:00

abstract：:Malignant hyperthermia is a rare autosomal dominant trait that predisposes affected individuals to great danger when exposed to certain anaesthetic triggering agents (such as potent volatile anaesthetics and succinylcholine). A sudden hypermetabolic reaction in skeletal muscle leading to hyperthermia and massive rhabd...

journal_title：Postgraduate medical journal

authors： Ben Abraham R,Adnet P,Glauber V,Perel A

更新日期：1998-01-01 00:00:00

abstract：:Six Arabs subjects (three postpubertal, two prepubertal and one pubertal) from three interrelated Omani families with male pseudohermaphroditism due to 5 alpha-reductase-2 deficiency were evaluated. These subjects had been raised as girls since birth as they were born with a clitoral-like phallus and ambiguous externa...

journal_title：Postgraduate medical journal

authors： al-Attia HM

更新日期：1997-12-01 00:00:00

abstract：:We present a 78-year-old woman with clinical acute hypopituitarism in whom pathologic findings showed lymphocytic hypophysitis and retroperitoneal fibrosis. Lymphocytic hypophysitis should be included in the differential diagnosis of hypopituitarism at any age. The association with idiopathic retroperitoneal fibrosis ...

journal_title：Postgraduate medical journal

authors： Alvarez A,Cordido F,Sacristán F

更新日期：1997-11-01 00:00:00

abstract：:The clinical features of acute chlorine gas inhalation, and its management are reviewed. Current medical views on the chronic effects of an acute overwhelming exposure on lung function (reactive airways dysfunction syndrome), and the more controversial field of lung disease secondary to repeated inhalations of lower c...

journal_title：Postgraduate medical journal

authors： Williams JG

更新日期：1997-11-01 00:00:00

abstract：:Retroperitoneal fibrosis, either idiopathic or associated with aortic inflammatory aneurysm, is a chronic fibrotic disease that causes progressive obstruction of ureters and vessels around the lower abdominal aorta. Treatment is often difficult (surgery) or hazardous (steroids). We report a case of a woman with retrop...

journal_title：Postgraduate medical journal

authors： Frankart L,Lorge F,Donckier J

更新日期：1997-10-01 00:00:00

abstract：:Postherpetic neuralgia is defined as pain persisting, or recurring, at the site of shingles at least three months after the onset of the acute rash. Thus defined, at least half of shingles sufferers over the age of 65 years develop postherpetic neuralgia. In addition to increasing age, less important risk factors for ...

journal_title：Postgraduate medical journal

authors： Bowsher D

更新日期：1997-10-01 00:00:00

abstract：:Digital clubbing has been a well recognised feature of several distinct clinical conditions, including respiratory, cardiac, and gastrointestinal diseases since the Hippocratic era. However, clubbing associated with Behçet's disease has not been reported before. We describe a case of clubbing in a young man with Behçe...

journal_title：Postgraduate medical journal

authors： Benekli M,Güllü IH

更新日期：1997-09-01 00:00:00

abstract：:Intraperitoneal free gas seen radiologically as air under the diaphragm nearly always indicates a perforated abdominal viscus that requires surgical intervention. Rarely, however, the presence of a pneumoperitoneum may not indicate an intra-abdominal perforation and thus may not require laparotomy. Such a situation is...

journal_title：Postgraduate medical journal

authors： Williams NM,Watkin DF

更新日期：1997-09-01 00:00:00

abstract：:The Mirizzi syndrome is an unusual presentation of gallstones which occurs when a gallstone becomes impacted in either Hartmann's pouch of the gallbladder or the cystic duct, causing obstruction of the common hepatic duct by extrinsic compression. The diagnosis of this syndrome is of importance because surgery in its ...

journal_title：Postgraduate medical journal

authors： Pemberton M,Wells AD

更新日期：1997-08-01 00:00:00

abstract：:Disc herniation at the thoracic the spine level is more common than generally thought. Localisation of pain may be vague and may erroneously point to cardiopulmonary, gastrointestinal, genito-urinary or even psychiatric disease. Magnetic resonance imaging is the investigation of choice, especially if spinal cord compr...

journal_title：Postgraduate medical journal

authors： Pal B,Johnson A

更新日期：1997-07-01 00:00:00

abstract：:Current maintenance immunosuppressive regimens for transplantation are based on three classes of drugs: corticosteroids, immunophilin-binding agents (eg, cyclosporin and tacrolimus), and antimetabolites (eg, azathioprine and mycophenolate). Drugs from the various classes inhibit the immune system at different points a...

journal_title：Postgraduate medical journal

authors： Vella JP,Sayegh MH

更新日期：1997-07-01 00:00:00

abstract：:The anticoagulant agents heparin and warfarin were introduced before the era of randomised clinical trials. As a result, the indications, dosages and monitoring techniques of these drugs have undergone re-evaluation in multiple clinical trials in the past years. Low molecular weight heparin has been developed, which h...

journal_title：Postgraduate medical journal

authors： Toh CH

更新日期：1997-05-01 00:00:00

abstract：:We describe two patients with diabetes mellitus and associated neuropathy, who presented with painless foot swelling and no history of trauma. X-Rays revealed recent underlying fractures-in one of a metatarsus, and the other of a proximal phalanx. These were assumed to be 'stress' fractures unassociated with pain beca...

journal_title：Postgraduate medical journal

authors： Gill G,Benbow S,Tesfaye S,Kaczmarczyk E,Kaye L

更新日期：1997-04-01 00:00:00

abstract：:Despite the remarkable advances in cardiovascular therapeutics over the past four decades, little impact has been made on either the incidence or mortality rate of congestive heart failure and it remains a major clinical and public health problem. Recent practice audits have suggested that proven efficacious therapies...

journal_title：Postgraduate medical journal

authors： McAlister FA,Teo KK

更新日期：1997-04-01 00:00:00

abstract：:Interstitial nephritis is an inflammatory process within the renal interstitium, and was one of the first observations made in the description of renal histopathology. Many different conditions are associated with an interstitial nephritis, and as a clinical diagnosis the term has little use unless causation is define...

journal_title：Postgraduate medical journal

authors： Dhillon S,Higgins RM

更新日期：1997-03-01 00:00:00

abstract：:Paget's disease of bone is a relatively common condition in the UK affecting up to 5% of the population over the age of 55 years with particularly high prevalence in the North West of England. The majority of those affected are asymptomatic. Its precise cause remains unknown, and until recently, choice of treatment of...

journal_title：Postgraduate medical journal

authors： Ooi CG,Fraser WD

更新日期：1997-02-01 00:00:00

abstract：:A patient suffering from typhoid fever with severe pancytopenia is presented. Bone marrow examination revealed extensive haemophagocytosis which possibly contributed to the pancytopenia. ...

journal_title：Postgraduate medical journal

authors： Sood R,Roy S,Kaushik P

更新日期：1997-01-01 00:00:00

abstract：:A patient with the unusual post mortem finding of myocardial metastatic carcinoid tumour without classical valvular or endocardial carcinoid disease is described. This rare occurrence may represent an aggressive type of carcinoid tumour, with metastatic disease occurring before the development of classical fibrous val...

journal_title：Postgraduate medical journal

authors： Davis G,Birbeck K,Roberts D,Naqvi N

更新日期：1996-12-01 00:00:00

abstract：:A clinical and laboratory survey of systemic lupus erythematosus was conducted in 33 Arab patients in the UAE. Arthropathy (91%) followed by renal involvement (54%) and haematological disorders (45.5%) were the major clinical manifestations. Discoid rash (3%) was the least common. Apart from headaches, other neuropsyc...

journal_title：Postgraduate medical journal

authors： al-Attia HM

更新日期：1996-11-01 00:00:00

abstract：:Cough is one of the commonest symptoms of lung disease and is a frequent problem encountered in general practice as well as in hospital practice. A wide range of disease processes may present with cough and definitive treatment depends on making an accurate diagnosis of the cause. A diagnostic work-up for patients wit...

journal_title：Postgraduate medical journal

authors： Chung KF,Lalloo UG

更新日期：1996-10-01 00:00:00

abstract：:A 24-year-old man with primary Sjögren's syndrome presented with xerophthalmia, xerostomia, and marked parotid swelling. He had a previous history of selective IgA deficiency and ulcerative colitis treated with sulphasalazine. Immunosuppression and withdrawal of sulphasalazine resulted in rapid resolution of the parot...

journal_title：Postgraduate medical journal

authors： Steuer A,McCrea DJ,Colaco CB

更新日期：1996-08-01 00:00:00

abstract：:The effective training of facilitator/ tutors is crucial to the success of a problem-based learning approach to medical education. New skills are needed to accomplish the change from giver of information to facilitator of learning, coach, and guide. This paper outlines considerations for the design of a tutor training...

journal_title：Postgraduate medical journal

authors： Wetzel MS

更新日期：1996-08-01 00:00:00

abstract：:Purtscher's retinopathy presents to the clinician as loss of vision in a patient with a history of a possible precipitating event such as recent major trauma, pancreatitis, childbirth or renal failure. The ophthalmological picture is one of ischaemia at the posterior pole with white patches of oedema and haemorrhages ...

journal_title：Postgraduate medical journal

authors： Buckley SA,James B

更新日期：1996-07-01 00:00:00

abstract：:We describe two cases of digoxin toxicity presenting with clinical and electroencephalographic evidence of encephalopathy without other features of digoxin toxicity. ...

journal_title：Postgraduate medical journal

authors： Greenaway JR,Abuaisha B,Bramble MG

更新日期：1996-06-01 00:00:00

abstract：:There is overwhelming evidence for the clinical efficacy of the influenza vaccine, especially in the elderly with chronic disease, reducing mortality and hospital admissions. There is also evidence to suggest that the influenza vaccine may be beneficial in the healthy elderly. There is some evidence to suggest that th...

journal_title：Postgraduate medical journal

authors： Morgan R,King D

更新日期：1996-06-01 00:00:00

abstract：:In the 1920s Moynihan described acute pancreatitis as "..the most terrible of all intra-abdominal calamities". He established a practice of immediate surgical intervention to remove the toxic products accumulating in the peritoneal cavity, and this treatment was endorsed by most centres, remaining the standard therapy...

journal_title：Postgraduate medical journal

authors： Skaife P,Kingsnorth AN

更新日期：1996-05-01 00:00:00

abstract：:Helicobacter pylori is associated with gastritis, peptic ulcers and gastric malignancies. Little attention has been paid to the possibility that it may also have a role in the pathogenesis of reflux oesophagitis. This is especially true in elderly patients who have life-long infection and provide an ideal group to stu...

journal_title：Postgraduate medical journal

authors： Liston R,Pitt MA,Banerjee AK

更新日期：1996-04-01 00:00:00

abstract：:Fibrosing colonopathy is a recently described complication of cystic fibrosis, of unknown aetiology but possibly related to treatment with high-dose pancreatic enzyme supplements. We have used a whole gut perfusion technique to study subclinical gut inflammation in cystic fibrosis patients; concentrations of haemoglob...

journal_title：Postgraduate medical journal

authors： Croft NM,Marshall TG,Ferguson A

更新日期：1996-03-01 00:00:00

abstract：:We describe the case of an acromegalic woman with primary infertility who was treated with clomiphene, and subsequently developed pituitary apoplexy. ...

journal_title：Postgraduate medical journal

authors： Walker AB,Eldridge PR,MacFarlane IA

更新日期：1996-03-01 00:00:00

abstract：:The relative prevalence of abnormalities of coronary flow reserve and oesophageal function was ascertained in 32 syndrome X patients with typical angina chest pain, a positive exercise test, and normal coronary arteries. Coronary flow reserve in response to a hyperaemic dose of papaverine was measured using an intraco...

journal_title：Postgraduate medical journal

authors： Chauhan A,Mullins PA,Gill R,Taylor G,Petch MC,Schofield PM

更新日期：1996-02-01 00:00:00

abstract：:Venepuncture is commonly regarded as a trivial procedure allocated to the most junior medical staff. The result of this policy is that junior doctors are required to perform a minimally invasive procedure on consenting patients without any structured venepuncture training or assessment. Consequently, inexperienced doc...

journal_title：Postgraduate medical journal

authors： McConnell AA,Mackay GM

更新日期：1996-01-01 00:00:00

abstract：:Medullary carcinoma of the thyroid commonly spreads to the lymphatics and later on in the disease process, to distant sites such as lung, liver and bone. Spread to the breast is rare (only two previous reported cases) and presents a major diagnostic dilemma. We report a case of metastatic medullary carcinoma of the th...

journal_title：Postgraduate medical journal

authors： Kiely N,Williams N,Wilson G,Williams RJ

更新日期：1995-12-01 00:00:00

abstract：:The nature of rehabilitation medicine is outlined in terms of its objectives, its methods, the patient groups which it seeks to help and its relationships to other specialties. Some major advances of recent years are discussed, such as the development of the impairment/disability/handicap framework. With particular em...

journal_title：Postgraduate medical journal

authors： Cozens JA,Chamberlain MA

更新日期：1995-11-01 00:00:00

abstract：:The effects of nilvadipine on the peripheral circulation in the lower extremities using a duplex system of two-dimensional colour and pulse Doppler ultrasonography were studied in 32 patients with type 2 diabetes mellitus and mild essential hypertension. The patients (19 men and 13 women) were randomly divided into tr...

journal_title：Postgraduate medical journal

authors： Sone H,Okuda Y,Mizutani M,Kawakami Y,Bannai C,Yamashita K

更新日期：1995-10-01 00:00:00